One City, Two Cultures

HypOxygen and Don Whitley Scientific are sponsoring a series of Keystone Symposia dealing with tumour micro environment (Vancouver), mitochondria and metabolism (Santa Fe), and immunity and inflammation (Olympic Valley). At the joint Keystone symposium on “Mitochondria, Metabolism and Heart Failure” and “Diabetes and Metabolic Dysfunction” in Santa Fe, research groups have come together to present their latest findings on metabolism.

Mitochondrial function is central to metabolism and energy sensing of the cells in all organs, and this joint meeting is bringing together researchers who gave talks on the regulation of metabolism under stress, mitochondrial quality control and dysregulated gluconeogenesis. Insight into the genes and the pathways controlling these processes at the cellular level is driving the search for more effective drugs.

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Expanding UKAS Calibration

More and more customers took advantage of our UKAS accredited temperature calibration work in 2014, particularly those customers working to the new clinical standard ISO15189:2012. Don Whitley Scientific has therefore invested in extra calibration equipment so that our team of service engineers hold all the relevant instrumentation to be able to carry out specific calibrations whilst on site. These are typically carried out at the same time as the service, which minimises disruption to the laboratory and therefore improves efficiency for all involved.

The investment in equipment during 2014 included a ‘high-end’ precision digital thermometer for our permanent laboratory, hand-held digital thermometers and precision stopwatches for our engineers.

Further investment in equipment will continue this year to ensure that we always have the correct instrumentation to meet our customers’ needs.

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Anaerobes. Where to Start?

Introduction to Clinical Anaerobic Bacteriology
Introduction to Clinical Anaerobic Bacteriology

To a newcomer, the field of anaerobic research can seem intimidatingly vast. With so many varieties of anaerobes, and differing means of culturing them, you may find yourself wondering whether the method you are using is really the most efficient and cost-effective.

The first thing you need to consider is the type of anaerobe you are cultivating, whilst aerotolerant organisms and facultative anaerobes will not be harmed by a small amount of oxygen, obligate anaerobes require a completely oxygen-free environment.

We have recently produced a useful reference guide: An Introduction to Clinical Anaerobic Bacteriology which enables the reader to isolate and identify 12 commonly occurring and clinically important anaerobic bacteria.

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Did You Know: Whitley Workstations are Ethernet-enabled for Remote Access?

Have you ever wanted to check the status of your Whitley Workstation when you were away from the lab? Well now you can. Most of our new workstations are Ethernet-enabled so you can dial in and access the touch-screen control panel from the other side of the building, or even from the other side of the world. This allows you to check the current operating conditions of the workstation and, if activated, view any of the graphical screens. If necessary, you can then make changes to the parameters, i.e. temperature, humidity, O2 and CO2 levels from wherever, whenever!

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Workstation Users Could be Entitled to £250

Whitley H35 Hypoxystation

Do you use a Whitley Workstation? You could be entitled to £250.

Our travel grant scheme has now been extended to include any Whitley Workstation. If you have used a Whitley Workstation in your work and have mentioned it on your poster or published paper, let us know and you could be entitled to a grant of £250.

We have a series of grants available to those who mention the use of any Whitley Workstation or Hypoxystation in a poster they wish to present or in a published paper. All we ask in return is a copy of your poster/paper so we can use it to help promote the range to others.

If we have a trade stand at the event where you will be presenting your poster, we can provide copies to everyone who visits our stand, should you want to do this.

To apply for this grant, please send a copy of your poster or paper along with your contact details to steve_robertson@dwscientific.co.uk. If you are presenting a poster, don’t forget to let us know the title of the event and the date you will be making your presentation.

Did You Know: The A55 is a Dual Temperature Workstation?

Whilst the Whitley A55 Anaerobic Workstation’s large capacity allows two people to work side-by-side in the same environmental conditions, this workstation is unique in our range as it can also be supplied with a central partition to separate the workstation into two chambers. This permits the user to select different temperature/humidity combinations for each side of the workstation.

Can I transfer samples between the two chambers internally?
A manually operated, sliding door within the partition allows for convenient sample transfer between the chambers.

What is the maximum temperature differential that can be achieved in each chamber?
A maximum temperature differential of approximately 8˚C can be achieved between the two chambers.

Can I restrict who can adjust the environmental conditions?

There are security levels in place to restrict who is authorised to adjust temperature and humidity.

How can I check the relative humidity inside the chamber?
The relative humidity inside each chamber, expressed as a percentage, is always displayed on the main screen.

For more information please contact us directly.

Charity Fundraising

Thanks to a mixture of bake sales and raffles, in 2014 we were able to raise over £1,000 for our chosen charities!

This year, we hope to do even better and will be pledging our support to Martin House Children’s Hospice and Marie Curie Cancer Care.

A huge “Thank You” to everyone who contributed last year.

marie-curie-cancer-care-logo1

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Importance of Culturing Cells in Hypoxia

 

Why is it important to be able to culture cells in low oxygen? In this video, renowned cell biologist, Dr Violaine See (University of Liverpool) details some of her recent work and explains the significance of a hypoxic environment in determining her results.

Dr See’s research focuses on hypoxia signalling, especially on the important role of hypoxia-inducible factor timing to control cell fate and drug resistance. Dr See (pictured left)  has used a Whitley H35 Hypoxystation for the past six years, and said of the machine:

“We are very happy with it, because it is reliable and we get an excellent support service.”